\begin{document}$ (448.1 \pm 2.9) \times 10^{6} $\end{document} \begin{document}$ \psi(3686) $\end{document} events collected with the BESIII detector, we perform the first search for the weak baryonic decay \begin{document}$ \psi(3686) \to \Lambda_c^{+} \bar{\Sigma}^- +c.c. $\end{document}. The analysis procedure is optimized using a blinded method. No significant signal is observed, and the upper limit on the branching fraction (\begin{document}$ \mathcal B $\end{document}) of \begin{document}$ \psi(3686) \to \Lambda_c^{+} \bar{\Sigma}^- +c.c. $\end{document} is set as \begin{document}$ 1.4\times 10^{-5} $\end{document} at the 90% confidence level."> Search for the weak decay <inline-formula><tex-math id="M1">\begin{document}${\boldsymbol \psi(3686) \boldsymbol\to \boldsymbol\Lambda_c^{+} \bar{\Sigma}^- +c.c.} $\end{document}</tex-math><alternatives><graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="//www.macurncorp.com/hepnp/article/app/id/91504ac9-618b-45ef-bf3f-40355435bfd3/CPC-2022-0353_M1.jpg"/><graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="//www.macurncorp.com/hepnp/article/app/id/91504ac9-618b-45ef-bf3f-40355435bfd3/CPC-2022-0353_M1.png"/></alternatives></inline-formula> -
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